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Dr. Sunita Gupta

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1. Dr. Sunita Gupta, Prof (SAG) and Head of the Department

Education Background:

  • Bachelor of Dental Surgery (BDS) from Gujarat University, Ahmedabad,Gujarat, 1991
  • Master of Dental Surgery (MDS) in Oral Diagnosis & Dental Radiology from Gujarat University, Ahmedabad, Gujarat, 1995
  • Fellow of International College of Dentists, 2005
  • Master of Business Administration (Health Care Administration) from University of Delhi, 2006
  • Selected and recipient of prestigious Commonwealth Fellowship (UK) 2002-2003
  • Selected and recipient Indo Hungarian Fellowship 2013

Research Interest Areas:

  • Oral Oncology
  • Oral Potentially Malignant Disorders
  • Tumor Markers
  • Clinical Trials in Oral Medicine
  • Laser Surgery and Cryosurgery
  • Advanced Treatment and Diagnostic Modalities
  • Bone Tumors and Pathologies
  • Benign Lesions of Oral Cavity
  • Oro-facial Pain
  • Temporomandibular Joint Disorders
  • Oral & Maxillofacial Imaging
  • Infectious diseases
  • Biomedical Waste Management
  • Infection Control
  • Noise Pollution 

Research Grants Raised:

CSIR projects:

  • Correlation between clinical symptoms, MRI findings and synovial fluid levels of TNF – a and matrix metalloproteinases in patients with temporomandibular joint internal derangement Amount: Rs. 38, 00, 000/- approximately
  • Therapeutic assessment of zerumbone/ nano zerumbone in combination with curcumin/ nano curcumin on oral cancer cell lines Amount: Rs. 38, 00, 000/- approximately
  • Evaluation of audiometric findings, pre and post salivary and serum cortisol levels and response to various treatment modalities in myofascial pain syndrome Amount: Rs. 38, 00, 000/- approximately

University Grants Commission Project:

  • Role of p53, COX – 2, NF -kB and associated cytokines (IL – 1a, IL – 6, IL – 8, TNF – a) for assessing the malignant potential of oral cancer and their association to therapeutic response in patients with oral lichen planus and radiation induced mucositis Amount: Rs. 14, 00, 000/- approximately
  • Indian Council of Medical Research : Supervisor Dr Sunita Gupta 
  • Funding Amount Rs. 25,000/- Post graduate Thesis Titles:
  • Dr Shikha : “Pre and post treatment expression of p53, iNOS and TGF β in potentially malignant oral disorders”
  • Dr Sinni “To Evaluate the expression of Cdk4, p16 and serum IL6 levels in oral lichen planus patients for assessing the malignant potential and inflammatory responses with various therapeutic modalities”
  • Dr Girish: “Correlation of expression of ALDH1, ALK1 and CALR with response to treatment in OSMF and OLP”

Research Work in the following CSIR Projects: Supervisor Dr Sunita Gupta

  • Correlation between clinical symptoms, MRI findings and synovial fluid levels of TNF – a and matrix metalloproteinases in patients with temporomandibular joint internal derangement – Research Associate Dr Khushboo
  • Therapeutic assessment of zerumbone/ nano zerumbone in combination with curcumin/ nano curcumin on oral cancer cell lines -Research Associate Dr Shriya
  • Evaluation of audiometric findings, pre and post salivary and serum cortisol levels and response to various treatment modalities in myofascial pain syndrome-Reseach Associate Dr Priyanka 

Dr Sunita Gupta , Principal Investigator in the following UGC Projects

  • Role of p53, COX – 2, NF -kB and associated cytokines (IL – 1a, IL – 6, IL – 8, TNF – a) for assessing the malignant potential of oral cancer and their association to therapeutic response in patients with oral lichen planus and radiation induced mucositis 

Supervision in the following Post graduate thesis

  • Pre and post treatment expression of p53, iNOS and TGF β in potentially malignant oral disorders
  • To Evaluate the expression of Cdk4, p16 and serum IL6 levels in oral lichen planus patients for assessing the malignant potential and inflammatory responses with various therapeutic modalities
  • Evaluation and expression of IL6 and GMCSF salivary biomarkers in OPMD and OSCC
  • Evaluation of apparent diffusion coefficient in diagnosis of salivary gland tumors
  • Role of endothelin -1 & EGFR biomarkers in malignant transformation of oral potentially malignant disorders
  • Clinical correlation and expression of Zeb1, Twist & E cadherin in patients with oral submucous fibrosis and oral cancer
  • To evaluate the treatment response and expression of Hmlh1, MDM2 and p63 in oral potentially malignant disease
  • Age estimation using intra-oral radiography of the root pulp and periodontal ligament of lower third molar in age group of 15 – 30 years in the population of Delhi
  • Evaluation of Attenuation Coefficient in CT & expression of bone resorption regulators RANKL & OPG in Odontogenic Tumors: A Comparative Study
  • Evaluation of diagnostic efficacy of Ultrasonography & expression of Chimerin & MMP-9 in Oral Submucous Fibrosis & Oral Cancer
  • Correlation of expression of ALDH1, ALK1 and CALR with response to treatment in OSMF and OLP
  • Radiographic assessment of development of 2nd & 3rd molar teeth using modified demirjian staging for age estimation
  • Evaluation of attenuation coefficients in CT and expression of activator proteins fra-1, c-jun, c-fos in odontogenic tumors: a comparative study
  • Correlation and expression of TGF beta1, SMAD4 and SMAD7 in OSMF and OSCC
  • Attenuation coefficient in peripheral slices and expression of Ki67, Syndecan -1 and VEGF in odontogenic cysts and tumors: A comparative study
  • Clinical correlation, response to treatment & immunoexpression with cross talk between c-JUN & TGF-β in oral submucous fibrosis & oral cancer
  • Comparison of two treatment modalities and role of SIRT3 & SSEA4 as critical regulators at the crossroads between OSMF and Oral Cancer
  • Survival analysis with role of RACK1 and RPS6 as novel prognostic biomarker for OSCC: A clinico pathologic study
  • Effectiveness of topical curcumin and topical pirfenidone in oral submucous fibrosis with pre & post treatment expression of JNK, ATF – 2 & TGF β
  • Morphologic analysis with computerized tomography and expression of braf and keratin 15 in odontogenic cysts and tumors: a comparative study 

Supervision of Departmental Project

  • Efficacy of various medical treatment modalities in management of Trigeminal Neuralgia: A randomized controlled clinical trial 

Research Publications:

  • Bhatt G, Gupta S, Ghosh S. Comparative efficacy of topical aloe vera and low – level laser therapy in the management of oral lichen planus: a randomized clinical trial. Lasers Med Sci 2022; 37(3): 2063 – 2070. doi: 10.1007/s10103-021-03480-1
  • Mohanty S, Dabas J, Verma A, Gupta S, Aadithya B Urs, Hemavathy S. Surgical management of odontogenic keratocyst: A 20-year Experience. Int J Oral
  • Maxillofac Surg, 2021; 50(9): 1168 – 1176
  • Verma P, Khera S, Gupta S. Evaluation of HPA Suppressive effects of clobetasol propionate ointment in the treatment of Oral Lichen Planus. Int J Sci Res, 2021; 10(7): 41 – 42
  • Khaira S, Verma P, Gupta S. Role of Sesame Oil Pulling in the Management of Oral Submucous Fibrosis: A Pilot Study. Acta Scientific Dental Sciences. 2020;
  • 109 – 112
  • Khera S, Gupta S. Zerumbone: A Magical Phytochemical. Int J Health Sci Res. 2020; 10(10): 73 – 9
  • Urs AB, Augustine J, Gupta S. Cemento-osseous dysplasia: Clinicopathological spectrum of 10 cases analyzed in a tertiary dental institute. J Oral Maxillofac Pathol. 2020; 24: 576
  • Kumar P, Surya V, Urs AB, Augustine J, Mohanty S, Gupta S. Sarcomas of the Oral and Maxillofacial Region: Analysis of 26 cases with Emphasis on Diagnostic
  • Challenges. Pathol Oncol Res. 2019; 25: 593 – 601 
  • Piyush P, Mahajan A, Singh K, Ghosh S, Gupta S. Comparison of therapeutic response of lycopene and curcumin in oral submucous fibrosis: A randomized
  • controlled trial. Oral Dis. 2018; 25: 73 – 79 
  • Gupta S, Kumar P, Kaur H, Sharma N, Gupta S, Saluja D, Bharti A, Das B. Constitutive activation and overexpression of NF-B/c-Rel in conjunction with p50
  • contribute to aggressive tongue tumorigenesis. Oncotarget. 2018; 9: 33011 – 33029
  • Gupta S, Piyush P, Mahajan A, Mohanty S, Ghosh S, Singh K. Fibrotomy with diode laser (980nm) and habit correlation in oral submucous fibrosis: a report of 30 cases. Lasers Med Sci. 2018; 33: 1739 – 45
  • Bhat ZI, Marwah A, Zafaryab M, Khurana N, Urs AB, Verma M, Garg V, Aggarwal AK, Gupta S, Rizvi MMA. Expression Analysis of p53 and Cyclooxygenase-2 in Oral Lichen Planus. Int J Health Sci Res. 2017; 7(3): 126 – 134
  • Gupta S, Ghosh S, Gupta S, Sakhuja P. Effect of Curcumin on the Expression of p53, Transforming Growth Factor–β and Inducible Nitric Oxide Synthase in Oral Submucous Fibrosis: A Pilot Study. J Invest Clin Dent 2016; 1 – 6
  • Marwah A, Iqbal Z, Zafaryab M, Verma M, Rizvi MMA, Gupta S. Profiling of Pro-Inflammatory Cytokines in Radiation Induced Oral Mucositis (RIOM) among
  • Indian Patients. Braz J Oral Sci. 2016; 15(4): 280 – 286
  • Goel S, Marwah A, Kaushik S, Garg V, Gupta S. Role of Serum Interleukin-6 in Deciding Therapy for Multidrug Resistant Oral Lichen Planus. J Clin Exp Dent.
  • 2015 October; 7(4): e477 – e482
  • Goel S, Khurana N, Marwah A, Gupta S. Expression of cdk4 and p16 in Oral Lichen Planus. J Oral Maxillofac Res. 2015; 6(2): e4
  • Mohanty S, Gupta S, Kumar P, Sriram K, Gulati U. Retrospective Analysis of Ossifying Fibroma of Jaw Bones over a period of 10 years with Literature
  • Review. J Maxillofac Oral Surg. 2014; 13: 560 – 67 

Research Awards:

  • Recipient of Indo-German award for the best fundamental Research in Oral Cancer and molecular biology at the 3rd International Oral Cancer Congress
  • Selected as a “Best All Rounder Women in Dentistry” at the 18th Asian Pacific Dental Congress
  • Recipient of Colgate Palmolive award
  • Selected and recipient of prestigious Commonwealth Fellowship (UK) 2002-2003
  • Selected and recipient Indo Hungarian Fellowship 2013 

Guided and Supervised the Post graduates research work and they won prizes in National Conferences

  • 1st Prize at 30th Indian Academy of Oral Medicine & Radiology National Conference from 23rd – 25th November 2018 at Pacific Academy of Higher Education Udaipur for best thesis paper “Evaluation of diagnostic efficacy of Ultrasonography & expression of Chimerin & MMP-9 in Oral Submucous Fibrosis & Oral Cancer”: Dr. Puneet Vats
  • 1st Prize at 33rd Indian Academy of Oral Medicine & Radiology National Conference from 8th – 10th December 2022 at KIIT Auditorium, Bhubaneswar, Odisha for paper “Efficacy of green tea extract in management of Oral Submucous Fibrosis – A randomized, prospective and comparative study”: Dr. Pavithra R
  • 2nd Prize at 33rd Indian Academy of Oral Medicine & Radiology National Conference from 8th – 10th December 2022 at KIIT Auditorium, Bhubaneswar, Odisha for paper “Survival analysis with role of RACK1 and RPS6 as novel prognostic biomarker for oral squamous cell carcinoma: A clinicopathologic study”: Dr. Chetna 
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