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Dr. Aadithya B Urs

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DR. AADITHYA B. URS

 

ACADEMIC QUALIFICATIONS:

  • BDS in 1996 from Govt. Dental College, Bangalore.
  • MDS (Oral Pathology) in 2000 from A.B. Shetty Memorial Institute of Dental Sciences, Mangalore.

RESEARCH INTEREST AREAS:

  • Oral squamous cell carcinoma, Oral potentially malignant disorders, Odontogenic tumours, Molecular pathology

RESEARCH PROJECTS UNDER CSIR:

  1. Association of Candida species and their genotypes in Oral Lichen Planus: a study in North Indian population
  2. Evaluation of gene polymorphism and gene expression of shh and pi3k gene in Ameloblastoma : a prospective study.


SUPERVISOR / CO SUPERVISOR IN MDS RESEARCH WORK: 

S.N o Thesis Title Name of Student Supervisor Co Supervisor Brief Outcome
1 p53 as an expression of aggressiveness in Odontogenic Keratocyst when compared to Ameloblastomas Dr. Sandeep Gupta Dr. Aadithya B. Urs   Completed
2 Analysis of cellular interactions in the basal cell region of Oral Lichen Planus-an Ultra structural study. Dr. Mayura Paul Dr. Aadithya B. Urs   Completed
3. Role of salivary superoxide dismutase in progression of OSMF Dr. Yuthicka Sirohi Dr. Aadithya B. Urs   Completed
4 Expression of HSP70,in Oral Lichen Planus. Dr. Nutan Tyagi   Dr. Aadithya B. Urs Completed
5 Reliability of histologic grading in epithelial dysplasias when compared with use of p53 and AgNORS. Dr. Anshuta Sahu   Dr. Aadithya B. Urs Completed
6 A polarizing microscopic study to analyze the zones of incipient caries by different media. Dr. Rupinder Kaur   Dr. Aadithya B. Urs Completed
7 Evaluation of MMP-9 and TIMP-2 in various histological subtypes of Ameloblastoma- Role in local invasiveness : An immunohisto chemical study. Dr. Kalpana Nunia Dr. Aadithya B. Urs   Completed
8 Association of macrophages with angiogenesis in oral epithelial Dr. Himanshi Chawla Dr. Aadithya B. Urs   Completed
  dysplasia, Oral Verrucous Carcinoma and Oral Squamous Cell Carcinoma: An immunohistochem ical study.        
9 Correlation of Cyfra 21-1 levels in saliva and serum with CK19 mRNA expression in Oral Squamous Cell Carcinoma Dr. Rewa Malhotra Dr. Aadithya B. Urs   Completed
10 Role of CYP1A1 and CYP2E1 gene polymorphism in Oral Submucous Fibrosis. Dr. Punyo Yaming Dr. Aadithya B. Urs   Completed
11 Cytokeratin and Fibronectin expression in Orthokeratinized Odontogenic Cyst: A comparative IHC study. Dr. Kirti Kureel Dr. Aadithya B. Urs   Completed
12 Comet Assay for Dr. Garima Dr. Aadithya B. Urs   Completed
  assessing DNA damage in buccal cells and peripheral blood leucocytes in oral Potentially Malignant and malignant disorders. Rawat      
13 Immunoexpressio n and genetic alteration of PTEN in pathogenesis of Ameloblastoma. Dr. Bhaskar Narayan Dr. Aadithya B. Urs   Completed
14 Assessment of interleukin-18 gene polymorphism and serum levels in oral lichen planus- A prospective case control study. Dr. Deepika Negi Dr. Aadithya B. Urs   Completed
15 Assessment of CX3CL1 chemokine and CD 57+ lymphocytes in Dr. Shivani Singh Dr. Aadithya B. Urs   Completed
  immune surveillance of Oral Squamous Cell Carcinoma.        
16 Assessment of platelet- lymphocyte ratio and neutrophil- lymphocyte ratio to predict lymph node metastasis in association with detection of occult metastasis using desmoglein- 3 in Oral Squamous Cell Carcinoma. Dr. Akanksha Uniyal Dr. Aadithya B. Urs   Completed
17 Comparative evaluation of DNA isolation from extracted teeth under different environmental conditions by two methods for forensic analysis. Dr. Azhar Ahmed Khan Dr. Aadithya B. Urs   Completed
18 Assessment of Dr. Anshul Dr. Aadithya B. Urs   Completed
  HIF-1Α and LOXL-2 expression in Oral Squamous Cell Carcinoma – An Immunohistochem ical Study Bharti      
19 Correlation of β- catenin and glypican 3 expression in oral squamous cell carcinoma- an immunohistochem ical study Dr Kiran Jot Dr. Aadithya B. Urs   Completed
20 Comparative evaluation of the accuracy of radiographic and histological age estimation methods in adult indians. Dr Manoj Kumar Dr. Aadithya B. Urs   Completed
21 Assessment of salivary mirna-184 and mirna-21 in oral squamous cell Dr Aarushi Garg Dr. Aadithya B. Urs   Completed
  carcinoma and oral potentially malignant disorders- a qrt pcr based case control study        
22 Evaluation of tissue based expression of mirna-155-5p and mirna-1246 in oral squamous cell carcinoma- a qrt pcr study Dr Maheshwari R Dr. Aadithya B. Urs   Completed
23 Asssessment of STAT 3 and ITGB6 expression in oral squamous cell carcinoma and their correlation with lymph node metastasis and overall survival- An immunohistochem ical study Dr Shivangni Rajoria   Dr. Aadithya B. Urs Completed
24 Human tissue expression of miRNA 196a and miRNA 196b by quantitative RTPCR in oral squamous cell carcinoma Dr Kuldeep Singh Dr. Aadithya B. Urs   Completed
25 Artificial Intelligence - Based Lymph Node Metastasis Detecti on in Oral Squamous Cell Carcinoma - A Case Control Study" Dr Sourendranath Basu   Dr. Aadithya B. Urs Ongoing
26 Assessment of Tumor Associated Tissue eosinophil and Interleukin-33 immunoexpressio n in OSCC and their correlation with overall survival : A Morphometry and IHC study Dr Rajiv Saini Dr. Aadithya B. Urs   Ongoing


DETAILS OF ALL ORIGINAL RESEARCH PUBLICATIONS:

S.No. Title
1. Singh S , Selvan Chokkalingam T, Pillai JP, Urs AB. Does third molar impaction affect age estimation in adolescent and young adults? A radiographic population based study. Medico-Legal Journal 2022. 0(0) 1–5 DOI: 10.1177/00258172221077725
2. Singh H , Kumar S, Urs AB, Kapoor S. Identifcation of sequence polymorphisms in the D-loop region of mitochondrial DNA as valuable biomarkers for salivary gland tumors: an observational study. The Egyptian Journal of Otolaryngology (2022) 38:22  https://doi.org/10.1186/s43163-022- 00208-y
3. Garg A, Guru SA,Koner BC,Augustine J, Urs AB.MO26-1 miR-21 and miR184 as early diagnostic miRs for oral squamous cell carcinomas and oral potentially malignant disorders. Annals of Oncology 33,S498
4. Ramamoorthy M, Guru SA,Koner BC,Kumar P, Urs AB.MO26-3. miR-155-5p and miR1246 as promising biomarkers in oral squamous cell carcinomas. Annals of Oncology 33, S498-S499
5. Garg A, Maheshwari R, Urs AB. Association of Oral Melanosis with Soft Tissue Pathologies: A Hospitalbased Observational Study. Journal of Clinical and Diagnostic Research. 2021 Nov, Vol- 15(11): EC15-EC18
6. Jot K, Urs AB, Kumar P. Does Loss of Immunohistochemical Expressionof Glypican 3 in Oral Squamous Cell Carcinoma Play a Role in the Wnt/beta-catenin Signaling Pathway?. Appl Immunohistochem Mol Morphol. 2021 Oct 1;29(9):693-699. doi: 10.1097/PAI.0000000000000955.PMID: 34091531
7. Sharma V, Nawal RR, Augustine J , Urs AB , Talwar S. Evaluation of Endosequence Root Repair Material and Endocem MTA as direct pulp capping agents: An in vivo study. Aust Endod J. 2021 Jul
  18. doi: 10.1111/aej.12542. Online ahead of print .PMID: 34278657.
8. Bharti A, Urs AB, Kumar P. Significance of HIF-1α Expression and LOXL-2 Localization in Progression of Oral Squamous Cell Carcinoma. Asian Pac J Cancer Prev 2021; 22 (2): 341-347
9. Mohanty S, Dabas J, Verma A, Gupta S, Urs AB, Hemavathy S. Surgical Management of the Odontogenic Keratocyst: A 20-year Experience. Int J Oral Maxillofac Surg. 2021 Mar 2:S0901- 5027(21)00056-4. doi: 10.1016/j.ijom.2021.02.015. Online
10. Urs AB, Jot K, Kumar M. Ghost Cell Characterization in Calcifying Odontogenic Cyst and Dentinogenic Ghost Cell Tumors: An immunohistochemical study. J Oral Biosci. 2020 Dec;62(4):336- 341. doi: 10.1016/j.job.2020.10.002. Epub 2020 Oct 12.PMID:
11. Urs AB, Augustine J, Gupta S. Cemento-osseous dysplasia: Clinicopathological spectrum of 10 cases analyzed in a tertiary dental institute. J Oral MaxillofacPathol 2020;24:576-7.
12. Khan AA , Urs AB, Augustine J, Singh H. Comparative forensic analysis of reverse root canal filing and conventional method for DNA isolation from extracted teeth under different environmental conditions: A prospective study. J Forensic Odontostomatol Dec 2020;38( 3) :35-41 ISSN :2219-674
13. Singh H, Narayan B, Urs AB, Polipall SK, Kumar S. A novel approach for extracting DNA from formalin-fixed paraffin-embedded tissue using microwave .Medical Journal Armed Forces India 2020 ; 76 :307 -311
14. Rawat G, Kureel K, Urs AB. An insight into crystallization test: A neoteric approach for screening premalignant and malignant lesions. J Can Res Ther 2020;16:440-4.
15. Narayan B, Urs AB, Augustine J, Singh H. Role of phosphatase and tensin homolog in pathogenesis of ameloblastoma: An immunohistochemical study. J Cancer Res Ther2020;16:513-6.
16. Narayan B, Urs AB, Augustine J, Singh H, Polipalli SK, Kumar S, Kapoor S. Genetic alteration of Exon 5 of the PTEN gene in Indian patients with ameloblastoma.Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Mar;127(3):225-230.
17. Negi D, Urs AB, Kumar P, Mahajan B, Singh H, Polipalli SK, Kapoor S. Assessment of Interleukin- 18 gene polymorphism and serum levels in oral lichen planus in an Indian population.. J Oral Pathol Med. 2019 Mar;48(3):244-250.
18. Kureel K, Urs AB, Augustine J. Cytokeratin and fibronectin expression in orthokeratinized odontogenic cyst: A comparative immunohistochemical study. J Oral MaxillofacPathol 2019;23:65-72.
19. Priya Kumar, Varun Surya, Aadithya B. Urs, J. Augustine, Sujata Mohanty , Sunita Gupta. Sarcomas of the Oral and Maxillofacial Region: Analysis of 26 Cases with Emphasis on Diagnostic Challenges. Pathology & Oncology Research 2019 Apr;25(2):593-601. doi: 10.1007/s12253-018-0510-9. Epub 2018 Oct 31.
20. Rawat G, Urs AB, Kumar P , Chakravarti A.DNA damage in buccal cells in oral PMDs and malignant disorders by comet assay: a comparison with blood leukocytes. Brazilian Journal of Oral Science Volume 18 2019 e191430
21. Garima Rawat, Aadithya B Urs, Anita Chakravarti, Priya Kumar.Evaluation of DNA Damage in Peripheral Blood Leukocytes in Oral Potentially Malignant and Malignant Disorders by Comet Assay. Clinical Cancer Investigation Journal, Year 2018, Volume 7, Issue 2 [p. 50-55]DOI: 10.4103/ccij.ccij_66_17
22. Chawla H, Urs AB, Augustine J. Association of Macrophages with Angiogenesis in Oral Epithelial Dysplasia, Oral Verrucous Carcinoma, and Oral Squamous Cell Carcinoma: An Immunohistochemical Study. Appl Immunohistochem Mol Morphol.2017Mar;25(3):203-
  208.doi10.1097/PAI.0000000000000284.
23. Bhat ZI, Marwah A, Md. Zafaryab Nita Khurana , Aadithya B Urs , Mahesh Verma , Vijay Garg , A.K. Agarwal , Sunita Gupta , M.M.A Rizvi.Expression analysis of p53 and cyclooxygenase-2 in oral lichen planus. Int J Health Sci Res. 2017; 7(3):126-134.
24. Kumar P, Augustine J, Urs AB. Odontogenic cysts and tumours- An institutional review of 736 cases. Journal of Dental Research 2016;95(A):Abstracts 1723
25. Malhotra R, Urs AB, Chakravarti A, Kumar S, Gupta VK, Mahajan B Correlation of Cyfra 21-1 levels in saliva and serum with CK19 mRNA expression in oral squamous cell carcinoma.Tumour Biol. 2016 Jul;37(7):9263-71. doi: 10.1007/s13277-016-4809-4.
26. S Arora, M Verma, SR Gupta, AB Urs, MS Dhakad& R Kaur. Phenotypic variability and therapeutic implications of Candida species in patients with oral lichen planus. Biotechnic & Histochemistry 2016 May;91(4):237-41. doi: 10.3109/10520295.2015.1127425. Epub 2016 Mar 16.
27. Nunia K, Urs AB, Kumar P. Interplay Between MMP-9 and TIMP-2 Regulates Ameloblastoma Behavior and Tooth Morphogenesis. Appl Immunohistochem Mol Morphol. May/June 2016 ; 24( 5): :364–372
28. Yaming P , Urs AB , Saxena A, Zuberi M. Roles of CYP1A1 and CYP2E1 Gene Polymorphisms in Oral Submucous Fibrosis. Asian Pac J Cancer Prev. 2016;17(7):3335-40.
29. Kumar P, Augustine J, Urs AB. Odontogenic cysts and tumours- An institutional review of 736 cases. Journal of Dental Research 2016;95(A):Abstracts 1723
30. Pathak H, Mohanty S, Urs AB, Dabas J. Treatment of Oral Mucosal Lesions by Scalpel Excision and Platelet-Rich Fibrin Membrane Grafting: A Review of 26 Sites. J Oral Maxillofac Surg. 2015
  Sep;73(9):1865-74. doi: 10.1016/j.joms.2015.03.041. Epub 2015 Mar 26.
31. Augustine J, Kumar P, Urs AB. Intra osseous ameloblastoma: an institutional experience and an insight into its rare variants.Head Neck 2015 July; 37(S1): E39
32. Chawla H, Urs AB, Augustine J, Kumar P. Characterization of muscle alteration in oral submucous fibrosis-seeking new evidence. Med Oral Patol Oral Cir Bucal. 2015 Nov 1;20(6):e670-e677
33. Aadithya B. Urs, Shelly Arora, Hanspal Singh. Intra-Osseous Jaw Lesions in Paediatric Patients: A Retrospective Study .Journal of Clinical and Diagnostic Research. 2014 Mar, Vol-8(3): 216-220.
34. AadithyaB.Urs, Priya Kumar, Shelly Arora. J. Augustine .Clinicopathologic and radiologic correlation of ossifying fibroma and juvenile ossifying fibroma—an institutional study of 22 cases. Ann Diagn Pathol. 2013 Apr;17(2):198-203.
35. Aadithya B. Urs, Jeyaseelan Augustine ,Himanshi Chawla. Aneurysmal Bone Cyst of the Jaws:Clinicopathological Study. J Maxillofac Oral Surg. 2013 July.
36. Nutan Tyagi, Devicharan Shetty, Aadithya B Urs. Altered expression of HSP70 in oral lichen planus . J Oral MaxillofacPathol 2012 ;16(2):189-94.
37. Shelly Arora., Priya Kumar, Aadithya B. Urs, J. Augustine. Unicystic Ameloblastoma: Clinical Pathological Analysis of 22 Cases . Acta Stomatol Croat. 2012; 46(3):230-240.
38. Priya Kumar, J. Augustine ,Aadithya B. Urs ,Shelly Arora.,Shalini Gupta, Vikrant Mohanty. Serum lipid profile in oral cancer and leukoplakia: correlation with tobacco abuse and histological grading. J Can Res Ther 2012; 8(3):384-8.
39. Vijay Wadhwan, Aadithya B Urs, Adesh Manchanda. Sex determination using three methodologies as a tool in forensic dentistry. Journal of Indian Dental Association January 2011; 5(1):77-80.
40. YuthickaSirohi, Devi Charan Shetty, Aadithya B Urs, Harish Chandra Rai. Profiling of antioxidant superoxide dismutase in saliva of oral submucous fibrosis patients to categorize its diagnosis in varying stages. Pak J Med Res Jul - Sep 2011;50(3):120-2
41. Aadithya B Urs, Devi Charan Shetty, Puneet Ahuja, Deepika Bablani, Adesh Manchanda. Asymptomatic Third Molar Removal? – A Clinical and Pathological Insight. Journal of Orofacial Sciences 2010; 2(1).4-8.
42. Devi Charan Shetty, Aadithya B. Urs, Harish Chandra Rai, Deepika Bablani, Nutan Tyagi. Orofacial Granulomatosis: A Case Report. Chirurgia Dec 2010;23(6):311-13.
43. Devi Charan Shetty, Aadithya B. Urs, Suhas Godhi, Sandeep Gupta. Classifying Odontogenic Keratocysts as Benign Cystic Neoplasms- A Molecular Insight into its Aggressiveness. J Maxillofac Oral Surg 2010;9(1):30-34.
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